Showing posts with label Mesothelioma. Show all posts
Showing posts with label Mesothelioma. Show all posts

Sunday, May 20, 2012

Mesothelioma Lawyers

Understand how to choose a lawyer for this disease, you should first understand the basics of the disease. In the simplest sense, mesothelioma is a cancer of the protective layers of the body cavities, known as the mesothelium.
These tissues have different names depending on the organs they protect. You have probably heard of the peritoneum–this is the covering around the stomach and intestines. Other organs and cavities have their own membranes as well.

Mesothelioma is a cancer of these tissues
. They often do not just affect the tissues–they affect the organs they surround and can spread elsewhere. This cancer is most often contracted by exposure to asbestos, a highly dangerous mineral often found in floors, ceilings, and some products.

Employers and landlords are supposed to protect you from asbestos, but often this does not happen. If you have mesothelioma you have probably been exposed to asbestos. If so, you should contact mesotheloma attorneys in your area to see if you have a case against the party responsible for your exposure.

If you have been diagnosed with mesothelioma, your oncologist may be your best source of names for attorney contacts. She will likely have already worked with them on cases and can tell you not only who specializes in your type of cancer but who is best and who is within a short distance from your home or work. If she does not have the right kind of specialist, there are other ways to find the right professional for your case.

You can check with other doctors who deal specifically deal with mesothelioma if your doctor is more of a general oncologist. These doctors may have worked more closely with mesothelioma lawyers in your area of southern California. You can also call local hospitals, various cancer support groups–area law schools are also excellent for references. Also check your union or professional group if you were exposed on the job.

Regardless of where you find your contacts, interview the lawyer, check on his or her background, and get references if you can. If you are ill, the last thing you need is more trouble.

Saturday, October 8, 2011

Mesothelioma Treatments

Pleural Mesothelioma Treatments
Treatment for mesothelioma can range from palliative care to curative attempts to beat the cancer. Some of the more common methods of treatment may include surgery, chemotherapy and radiation therapy. One approach, called multimodality treatment, combines all three to create an aggressive approach towards fighting the cancer. Patients receiving such treatment are usually diagnosed during the first stage of development and have a higher chance of positively responding to treatment.
Clinical trials testing new medications and treatment methods may also be an option for some pleural mesothelioma patients. All treatment medications go through a clinical trial before being deemed safe for general use and patients sometimes enter a clinical trial with the hope for a cure. Clinicaltrials.gov offers a comprehensive list of mesothelioma trials that are recruiting patients and trials that are already in progress.
Some patients may experience remission of the cancer after receiving treatment, but this does not mean the cancer has been cured. In most cases, pleural mesothelioma tumors that go into remission often come back at a later date. Some researchers believe remission after treatment may be caused by changes in the immune system.

Mesothelioma Hope: Improving Prognosis and Survival

On the diagnostic side, scientists have found mesothelioma tumor markers in the blood as clues that reveal whether or not mesothelial tumors are forming in the body. Tests such as the Mesomark assay and other mesothelin screening devices are becoming available which make it possible to gauge a patient’s likelihood of developing pleural mesothelioma. This offers a chance for obtaining early detection as well as effective surgical treatment.
Therapeutically, the chemotherapeutic drug Onconase was found in 2006 to make a significant contribution to survival periods when applied as part of a standard anticancer regimen. Onconase’s maker was successful in applying for orphan-drug status, which is a special marketing status to encourage the development of drugs that will help a relatively small number of people. In 2007, studies indicated Onconase may also have a preventive effect against mesothelioma. Further research and studies are yet to be completed, but this and other drugs give some hope of therapeutic progress and perhaps someday leading to a mesothelioma cure.
Although only 2,000 to 3,000 people develop malignant mesothelioma each year in the United States, there has been an upsurge in research and therapeutic experimentation for the cancer. Pleural mesothelioma has the potential to be cured to some degree (remission) if it is detected early, but most patients are diagnosed during the advanced stages of development. As a result, research has equally been focused on finding ways to detect mesothelioma as well as how to treat it.
If you would like to learn more about pleural mesothelioma treatment options, please fill out the form on this page to receive a complimentary informational packet in the mail.

Sources:
  1. B. W. Robinson et al., “Mesothelin-family Proteins and the Diagnosis of Mesothelioma,” Lancet 362, no. 9396 (15 November 2003): 1612–6.
  2. National Institute of Health, “Clinical Trials http://www.clinicaltrials.gov/
  3. Raffit Hassan et al., “Mesothelin: A New Target For Immunotherapy,” Clinical Cancer Research 10 (15 June 2004): 3937–42, http://clincancerres.aacrjournals.org/cgi/reprint/10/12/3937.
 

Sunday, October 2, 2011

Cancer Mesothelioma

Mesothelioma is an aggressive cancer affecting the membrane lining of the lungs and abdomen.
Malignant mesothelioma is the most serious of all asbestos-related diseases. Although uncommon, mesothelioma cancer is no longer considered rare. The primary cause and risk factor for mesothelioma is exposure to asbestos.
Making a correct mesothelioma diagnosis is particularly difficult for doctors because the disease often presents with symptoms that mimic other common ailments. There is no known cure for mesothelioma, but treatments such as surgery and chemotherapy have helped to improve the typical mesothelioma prognosis.
Pleural mesothelioma (affecting the lung’s protective lining in the chest cavity) represents about three quarters of all mesothelioma incidence. Peritoneal mesothelioma which affects the abdominal cavity and pericardial mesothelioma, which affects the cardiac cavity, comprise the remainder. Testicular mesothelioma is extremely rare and is typically presents with metastases of the peritoneal variety. There are three recognized mesothelioma cell-types. Between 50 and 70% of all mesotheliomas are of the epithelial variety. While prognosis is generally poor, it is considered less aggressive than sarcomatoid mesothelioma and biphasic mesothelioma, which comprise the remainder of cell type diagnoses.

The cavities within the body encompassing the chest, abdomen, and heart are surround by a membrane of cells known as the mesothelium. Mesothelial cells assist in general organ functions. The mesothelium is particularly important to organs that are commonly in motion, such as expansion or contraction of the lungs, stomach, or heart. Lubrication from the mesothelial cells allows free range of motion within the body. The mesothelium of the chest, abdomen, and cardiac cavity are called the pleura, the peritoneum, and the pericardium, respectively. Each of these groupings of mesothelial cells are extremely critical to the functions of the body structures which they encompass.
Malignancies (cancerous tumors) occurring within the mesothelial membranes are known as malignant mesothelioma, or simply mesothelioma. Benign tumors of the mesothelium are known to occur, but are much rarer than the more common malignant cancer.
While tumors of the mesothelium were first recognized in the late 18th century, it was not until the middle of the 20th century that this particular cancer was studied and examined with more detail. It was at this time where suspicions of the cancer’s causal relationship with asbestos exposure became more substantiated. A joint research venture through the Department of Thoracic Surgery at the University of the Witswater and/Johannesburg General Hospital in South Africa provided the most compelling evidence of the nexus between asbestos exposure and the development of pleural mesothelioma.
Incidence of mesothelioma is still quite rare, with only 2,500-3000 diagnoses in the United States each year. There was a spike in reported diagnoses between 1970 and 1984, which has been attributed to the latency period between diagnosis and the height of industrial exposures, which occurred roughly 40-60 years prior to this time. Exposure was common in nearly all industries but was particularly common in the WWII-era military industrial cycle, including Navy Shipyards.
Although this cancer is much more common in men over the age of 60 (largely attributed to the industrial exposures within male-dominated industries), mesothelioma in women and children has been described as well. Mesothelioma causes for diagnosis in women and children are mainly attributed to secondary exposure to asbestos, as it was not uncommon for men to bring asbestos back into the home on their body or clothing if proper cleaning facilities were not available on site.

Mesothelioma is diagnosed through a comprehensive combination of biopsy and imaging scans.
Mesothelioma can be a difficult malignancy to diagnose because the symptoms and pathology of the disease closely resemble other respiratory conditions. For this reason, misdiagnosis is not uncommon in mesothelioma patients. Symptoms of mesothelioma include chest pain, chronic cough, effusions of the chest and abdomen, and the presence of blood in lung fluid.
Diagnostic surgeries, including a biopsy, will typically be required to determine the type of malignant cells that are present in the body. Typically a body imaging scan, including a magnetic resonance image (MRI) or computer topography (CT scan) will be required to determine the extent and location of the disease.
Mesothelioma patients are generally referred by their personal physicians to one of the many renowned mesothelioma doctors in the United States. These oncologists are well versed in the disease behavior and pathology and are the most familiar with cutting-edge mesothelioma treatment options. Dr. David Sugarbaker of the Brigham and Women's Hospital, an extension of Harvard University and the Dana Farber Cancer Institute in Boston, MA, is at the forefront of mesothelioma treatment through the International Mesothelioma Program.

While mesothelioma is typically advanced at diagnosis, treatment options are available.
Mesothelioma, while certainly an aggressive disease, is a manageable malignancy. While there is no cure for the cancer, mesothelioma treatment options including surgery, chemotherapy, and radiation therapy are available for many patients. While a combination of Alimta® and Cisplatin is currently the only FDA approved chemotherapy regimen, several clinical trials are currently in progress utilizing other drugs including Gemcitabine and Onconase, with many showing dramatically improved results in certain cancer patients.
Radiation therapy is also utilized, but typically in conjunction with other treatment methods like surgery and chemotherapy. Surgical resection of mesothelioma is possible in early-stage-diagnosed patients. Aggressive surgeries such as extrapleural pneumonectomy can extend survival rates far beyond previously-thought timeframes. Diagnostic and palliative surgeries such as pleurocentesis and pleurodesis are also common in patients of malignant mesothelioma cancer.
Alternative therapies have also been used effectively by many mesothelioma patients to assist in managing symptoms of the disease and conventional treatments. These treatments are mainly preferential but can be extremely valuable to many patients.

Mesothelioma is caused by exposure to asbestos.
Mesothelioma is only caused by exposure to asbestos, though cases have been documented in children or other individuals with no asbestos history. Asbestos is a microscopic and naturally-occurring mineral that lodges in the pleural lining of the lungs and the peritoneal lining of the abdominal cavity. In most cases, several years will pass (up to 60) before mesothelioma develops in those who had been exposed to asbestos.
In many cases, those individuals diagnosed with mesothelioma that have been known to be exposed to asbestos may be eligible for financial compensation from asbestos manufacturers for their illness. Those who have been diagnosed with mesothelioma and were exposed to asbestos should fill out the brief form on this page. We'll rush you a complimentary mesothelioma and asbestos exposure information kit detailing new mesothelioma treatments, active clinical trials, top doctors, as well as how to obtain compensation for asbestos-related health conditions like mesothelioma.
 

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